What effect do calcium channel blockers have on heart rate?

Calcium channel blockers primarily serve to reduce the heart rate by inhibiting the influx of calcium ions into the heart's muscle cells. Calcium plays a crucial role in the contraction of the heart muscle; by blocking calcium channels, these medications reduce the strength of heart contractions and slow down the conduction of electrical impulses within the heart. This mechanism is particularly beneficial in conditions such as hypertension and certain arrhythmias, as it helps to lower blood pressure and manage irregular heartbeats.

As a result of this action, calcium channel blockers typically lead to a decreased heart rate, which is important for patients in managing their cardiovascular health. The therapeutic goals of these drugs often include decreasing the workload on the heart and improving overall cardiac efficiency.